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In-vitro assay Development

In-vitro Biology: Models & Platforms for Assays

Within our Integrated Drug Discovery portfolio, our In vitro Biology models and platforms epitomize precision and innovation, driving transformative advancements in drug development. Our assay capabilities are meticulously structured across four primary verticals, each meticulously designed to tackle specific research needs.

Our Platform Technology encompasses a diverse array of assay types, leveraging cutting-edge methodologies that span the spectrum from biochemical to cell-based assays, ensuring comprehensive insights into drug interactions and mechanisms. Target Class specialization allows us to tailor assays to intricate molecular targets, offering nuanced perspectives crucial for therapeutic breakthroughs. Our proficiency spans an extensive range of Therapeutic Areas, enabling us to customize assays tailored to the unique challenges of each therapeutic landscape. Furthermore, our expansive models cater to diverse disease contexts, spanning Oncology, Inflammation, Infectious Diseases, Respiratory Diseases, Metabolic Disorders, and more. This comprehensive integration of models and platforms underscores our commitment to delivering pioneering solutions at the forefront of drug discovery.

In-vitro Biology: HTS Capabilities

High Throughput Screening (HTS) stands as the cornerstone of our Integrated Drug Discovery capabilities. Our HTS platform empowers rapid and systematic screening of vast compound libraries, accelerating the identification of potential drug candidates. With state-of-the-art technologies, our Reagent Generation process ensures the availability of high-quality tools vital for robust screening assays.

We offer versatile throughput screening solutions, facilitating the examination of compounds against a diverse array of targets encompassing various therapeutic areas. Our flexible Assay Formats cater to different screening needs, whether biochemical, cellular, or functional assays, ensuring a tailored approach for each project. Seamless Data Transfer processes enable swift and secure handling of screening data, optimizing efficiency. Assay Readouts encompass a range of sophisticated methods, providing comprehensive insights into compound interactions, allowing us to streamline the drug discovery journey towards transformative outcomes.

In-vitro Biology: Protein Production Capabilities

  • High-throughput purification purifying 30 protein per week
  • Membrane proteins such as VLPS, especially GPCRs & other receptors.
  • High-throughput expression screening and optimization in 96-well format
  • Low endotoxin protein purification
  • Characterization and validation of the proteins by SEC, Western, ELISA, BIAcore, FACS, IEF, 2D
  • Functional validation of protein produced by various assay platforms

Protein Production Capacities and Timelines

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