As a strategic partner, we support all your medicinal chemistry efforts through Hit identification to candidate selection. We demonstrate our expertise through efficient hypothesis-driven design and synthesis of compounds. They are optimized in rapid development through customized compound screening cascades.
Factors contributing to our medicinal chemistry group’s success include:
- Co-location with analytical chemistry, computational chemistry, biology, DMPK, formulation and in vivo pharmacology.
- Experienced chemists with the required skill set for developing synthetic routes for fast delivery of novel target compounds.
- Highly efficient library synthesis platform to enable rapid SAR expansion in a high throughput manner.
- State-of-the-art visualization and analysis tools used in our DMTA cycle.
- Continual scientific internal training programs, across all levels, to ensure upskilling of the AIDD scientific pool.
- Tailored resource allocation to match skill sets and experience of chemist towards specific program requirements.
- Each medicinal chemistry project receives a designated senior scientific team leader who is responsible for leading all the scientific activities in a matrix environment. This enables operational excellence and good scientific communication both within Aragen team and with our partners.
