Extensive institutional knowledge in diverse synthetic technologies enables us to build differentiating chemistry platforms. Aragen’s specialty chemistry teams synthesize highly complex molecules with structure characterization and corroboration, using advanced analytical tools.
A dedicated group handles carbohydrates such as oligosaccharide building blocks, complex oligosaccharides (up to octamers), glycophosphatidylinositol (GPI), glycosylated amino acids and glycoconjugates, providing novel targets for drug development programs.
Our team enables diverse and complex nucleoside/nucleotide chemistry, with demonstrated expertise in the creation of phosphoramidate prodrugs using ProTide technology.
Aragen scientists are experienced in the application of organoboron reagents to enable chemical transformations.
Leveraging our scientific experience in design and synthesis, we provide valuable proteolytic molecules for preclinical and lead optimization requirements.
We offer expertise in synthesis of chromophoric and non-chromophoric lipids to address any potential permeability challenges in the implementation of delivery tools for precision medicine.
We have developed vast experience in the synthesis of deuterated compounds in various reaction types, to understand reaction kinetics and mechanism, drug metabolism, improve PK profiles and the structural elucidation of macromolecules.
