Viral vectors (Lentiviral and Adeno-associated virus) are the most common gene delivery tools for hard to transfect and non-dividing cells. Cell and Protein Sciences provides wide range of viral vector production and testing services for preclinical studies.
Lentivirus (LV)
Lentivirus is a type of retrovirus containing single-stranded RNA genome. Lentivirus has been widely used as gene delivery tool for permanent integration of target gene into cells. We have capability to produce research grade high quality lentivirus.
Titer >107 IFU/mL leading to high transduction performance
Mycoplasma tested
Quality testing for expression by Western blot/ ELISA/ FACS
Timeline: 3-4 weeks*
* Excluding gene synthesis
Adeno-associated virus (AAV)
AAV is a non-enveloped, single-stranded DNA virus that can deliver the gene to both dividing and non-dividing cells. AAV has been one of the preferred gene delivery tools for gene therapy. Cell and Protein Sciences at Aragen has established the platform for producing high quality research grade AAV particles to support your research and development needs.
Why Aragen?
Optimized platform to produce multiple serotypes
High quality AAV particles
In-house AAV plasmid preparation and gene validation by sanger sequencing