Acute and chronic pain remain significant health problems despite tremendous progress in the understanding of their basic mechanisms. Studies conducted using intact animals allow the examination of the multidimensional nature of pain. Aragen scientists have developed various animal models to evaluate the efficacy of novel drug candidates against inflammatory, neuropathic and cancer pain.
Neuropathic Pain Models
Effect of tramadol on CCI (chronic constructive injury)-induced neuropathic pain in rats
Effect of gabapentin on SNL (spinal nerve ligation)-induced neuropathic pain in rats
Paclitaxel-induced polyneuropathic pain in rats
Streptozotocin-induced polyneuropathic pain in rats
Post-operative Pain Models
Brennan model of post-incisional pain in rats and mice
Inflammatory Pain Models
Complete Freund’s Adjuvant (CFA)-induced pain in rats
