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Solutions Large Molecules Discovery Biology In Vivo Pharmacology Metabolic Diseases

Metabolic
Diseases

Disease
Models

Cardiovascular and Metabolic Diseases, also known as lifestyle diseases, are the leading causes of morbidity and death in much of the modern world. The two major underlying causes are disorders of lipid metabolism, and metabolic syndrome that includes high blood pressure, high blood sugar, high fat and abnormal cholesterol. The ability to develop animal models that closely mimic the human disease condition is critical to advancing ameliorative or therapeutic treatments.

  • Obesity
    • Corn oil-induced dyslipidemia
    • Intralipid-induced dyslipidemia
    • Ghrelinemia model
    • Diet induced obesity (DIO)
  • Non-Alcoholic Steatohepatitis (NASH)
    • Streptozotocin (STZ)+high fat diet (HFD)-induced NASH
    • AMLN (Amylin Liver NASH) model in mice
  • Kidney Disease (CKD)
    • Unilateral ureteral obstruction (UUO)
    • 5/6 Nephrectomy in rats
  • Cardiovascular Disease
    • Monocrotaline-induced pulmonary arterial hypertension (PAH)
    • Bleeding time model of hemostasis in rats

FAQ

Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo. Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit

Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo. Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit

Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo. Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit
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