Brochure

Small Molecule Process R&D and Manufacturing

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To consistently deliver value-added scientific solutions with speed and quality, while ensuring safety and compliance.

Chemistry and Technologies

• Coupling Chemistry (Heck, Suzuki)
• Fluorination/Bromination
• Hazardous Chemistry
  • Azide
  • Cyanations
  • Nitrations
  • Lithium/Borane
  • DIBAL/Sodium Borohydride
  • POCl₃
• Peptides
• Pressure reductions/reactions (up to 25 bar)
• Chemo/Biocatalysis
• Flow processing
• Large Scale Chromatography

Operational Capabilities

• Active across three sites for security of supply
• 9 process blocks, 265+ KL capacity across three
  site 100L to 6000L, SS, GLMS, Hastelloy
• Milling
• cGMP and Non-GMP available
• HPAPI facility – to 1 µg / m3 (OEB 4)
• Operating pressure: full vac to 25 bar
• Operating temperature: -80^oc to 170^oc
• World class analytical support
• Comprehensive set of analytical capabilities
  performed 100% in-house (nGMP& GMP)

Highlights

• 3000+ scientists
• 450+ global clients
• Collaborations with 7 out of the 10 top pharma companies
• 74 NCE projects
• Sales diversity – North America (60%), Europe (30%), Asia Pacific (10%)
• Over 15 independent customer audits in FY 2020-21

Formulation Development

• Salt/Co-crystal/Polymorph studies
• Solid orals, liquids, injectable, ophthalmic and semisolids
• Integrated DS/DP development & supply
• Supported by multiple state-of-the-art facilities
• World-class scientific talent pool
• Culture of safety and compliance always

Regulatory and EHS